Zinc tetranitrophthalocyanine: isomer separation and photophysical photobiological evaluation in J774A tumor cells.

Abstract

The synthesis of zinc tetranitrophthalocyanine (T4NO2ZnPc) was carried out and two structural isomers (C2v and Cs) were separated by column chromatography and characterized by 400 MHz proton nuclear resonance spectroscopy and absorption spectroscopy. The photophysical and photobiological parameters for isomers C2v and Cs were determined in solution and in the presence of macrophage cell culture (J774A). The results obtained clearly indicated that the photophysical, photochemical and photobiological properties of the two isomers were different and each isomer showed a different biological behavior.

Copyright © 2003 Society of Porphyrins & Phthalocyanines.

Citation

Lunardi, C.N., Rotta, J.C. and Tedesco, A.C., 2003. Zinc tetranitrophthalocyanine: isomer separation and photophysical photobiological evaluation in J774A tumor cells. Journal of Porphyrins and Phthalocyanines, 7(07), pp.493-499.

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Categories: Medical & Pharmaceutical

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