A Nano-Filter-Integrated CMOS Image Sensor for Fluorescent Biomedical Imaging.
3 January 2019
This paper presents a fluorescent image sensor with the integrated plasmonic nano-filter using metal layers in CMOS. The readout circuit is fully integrated with a high-gain pixel-level capacitive trans-impedance amplifier (CTIA), column-level amplifier, and correlated double sampling (CDS).
The nano-filter achieved 51-dB simulated rejection ratio for 467-nm excitation light and 820-nm emission light. Considering low photodiode quantum efficiency and interference, a 24.2-dB system rejection ratio was achieved in measurement. In addition, liquid samples with/without PbS quantum dots (QDs) can be identified with 22-dB transmittance difference.
Jiang, Y., Yu, H., Fu, X., Hettiarachchi, C., Xu, H., Li, Y., Nguyen, T.H., Dong, L., Dang, C. and Zhang, Q., 2018, October. A Nano-Filter-Integrated CMOS Image Sensor for Fluorescent Biomedical Imaging. In 2018 IEEE Biomedical Circuits and Systems Conference (BioCAS) (pp. 1-4). IEEE.
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